BDBM50092749 CHEMBL3586324

SMILES COc1cc(cc2CN(Cc3cccc(c3)C#N)CCOc12)-c1csc2ccccc12

InChI Key InChIKey=FINCORCEGSQCIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092749   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50092749(CHEMBL3586324)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50092749(CHEMBL3586324)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed