BDBM50092723 CHEMBL3586342

SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2cc(Cl)ccc12

InChI Key InChIKey=WESWWOOIRSVBJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092723   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50092723(CHEMBL3586342)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50092723(CHEMBL3586342)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed