BDBM50092656 2-[4-(2,4-Diamino-pteridin-6-ylmethoxycarbonyl)-benzoylamino]-pentanedioic acid::CHEMBL327066

SMILES Nc1nc(N)c2nc(COC(=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=WNHAUPDSBGEACT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092656   

TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092656(2-[4-(2,4-Diamino-pteridin-6-ylmethoxycarbonyl)-be...)
Affinity DataIC50: 120nMAssay Description:Ability to inhibit recombinant rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092656(2-[4-(2,4-Diamino-pteridin-6-ylmethoxycarbonyl)-be...)
Affinity DataIC50: 3.10E+3nMAssay Description:Ability to inhibit recombinant human dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092656(2-[4-(2,4-Diamino-pteridin-6-ylmethoxycarbonyl)-be...)
Affinity DataIC50: 120nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed