BDBM50092485 4-methyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one::8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quinolin-3-one::CHEMBL118446

SMILES CC1=C2CCc3cc(Cl)ccc3N2CCC1=O

InChI Key InChIKey=DWGUKGCMIQALCV-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50092485   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50092485(8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataIC50: 5.80nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50092485(8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50092485(8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataIC50: 41nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase type I in human scalp homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50092485(8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataIC50: 41nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50092485(8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataKi:  2.70nMAssay Description:Inhibition constant against recombinant Steroid 5-alpha-reductase type I expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed