BDBM50092380 CHEMBL118896::[1-(3H-Imidazol-4-ylmethyl)-3-methyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone

SMILES CC1CN(Cc2cnc[nH]2)c2ccccc2CN1C(=O)c1cccc2ccccc12

InChI Key InChIKey=XTZAHDKEADCAKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092380   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50092380([1-(3H-Imidazol-4-ylmethyl)-3-methyl-1,2,3,5-tetra...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of purified recombinant human farnesyltransferase (FT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed