BDBM50092355 3-Benzyl-1-(3H-imidazol-4-ylmethyl)-4-methanesulfonyl-7-pyridin-4-yl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine::CHEMBL330815

SMILES CS(=O)(=O)N1Cc2cc(ccc2N(Cc2cnc[nH]2)C[C@H]1Cc1ccccc1)-c1ccncc1

InChI Key InChIKey=FRGOPLSOHOTEEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092355   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50092355(3-Benzyl-1-(3H-imidazol-4-ylmethyl)-4-methanesulfo...)
Affinity DataIC50: 16nMAssay Description:Inhibition of purified recombinant human farnesyltransferase (FT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed