BDBM50092198 CHEMBL3580743

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccc(F)cc2F)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O

InChI Key InChIKey=ARPMOQQOTWEYPJ-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50092198   

TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50092198(CHEMBL3580743)
Affinity DataIC50: 110nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50092198(CHEMBL3580743)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human recombinant mu opioid receptor expressed in CHO cells co-expressing C-terminally modified GGalphaqi5 assessed as stimulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50092198(CHEMBL3580743)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50092198(CHEMBL3580743)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50092198(CHEMBL3580743)
Affinity DataIC50: 0.420nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50092198(CHEMBL3580743)
Affinity DataEC50:  126nMAssay Description:Agonist activity at human recombinant delta opioid receptor expressed in CHO cells co-expressing Galphaq66Di5 assessed as stimulation of calcium rele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed