BDBM50092156 CHEMBL3582452

SMILES CC1(CC1)n1c(nc2ccc(F)cc12)-c1cccnc1

InChI Key InChIKey=QSLWQORQJVXQRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092156   

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092156(CHEMBL3582452)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of human CYP11B1 expressed in V79 cells incubated for 1 hr before 11-deoxycortisol substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092156(CHEMBL3582452)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed