BDBM50092015 (10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraene-11-thione::CHEMBL63262

SMILES CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=S)c23

InChI Key InChIKey=RVIJQMOQZFCSHL-UHFFFAOYSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50092015   

TargetProtein kinase C eta type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C eta C1b domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C epsilon C1b domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  62nMAssay Description:Binding affinity for Protein kinase C theta C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C delta C1b domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C beta C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  226nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C beta C1b domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  262nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C alpha C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  288nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C gamma C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  296nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C gamma C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  2.14E+3nMAssay Description:Binding affinity for Protein kinase C alpha C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  2.16E+3nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C eta C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  2.95E+3nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C delta C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092015((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...)
Affinity DataKi:  3.86E+3nMAssay Description:Binding affinity for Protein kinase C epsilon C1a domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed