BDBM50091956 CHEMBL292124::{2-[2-(2-Dimethylamino-ethyl)-indolo[3,2-b]quinolin-10-yl]-ethyl}-dimethyl-amine

SMILES CN(C)CCc1ccc2nc3c(cc2c1)n(CCN(C)C)c1ccccc31

InChI Key InChIKey=GKUZEDXGDACXNS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091956   

TargetTelomerase reverse transcriptase(Human)
Reading University

Curated by ChEMBL
LigandPNGBDBM50091956({2-[2-(2-Dimethylamino-ethyl)-indolo[3,2-b]quinoli...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against human ovarian cancer cell (A2780 cells) TelomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Reading University

Curated by ChEMBL
LigandPNGBDBM50091956({2-[2-(2-Dimethylamino-ethyl)-indolo[3,2-b]quinoli...)
Affinity DataIC50: 1.58E+10nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTelomerase reverse transcriptase(Human)
Reading University

Curated by ChEMBL
LigandPNGBDBM50091956({2-[2-(2-Dimethylamino-ethyl)-indolo[3,2-b]quinoli...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Reading University

Curated by ChEMBL
LigandPNGBDBM50091956({2-[2-(2-Dimethylamino-ethyl)-indolo[3,2-b]quinoli...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed