BDBM50091901 1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-4-phenyl-piperazine::CHEMBL64325

SMILES COc1ccc(Br)cc1-c1nc(CN2CCN(CC2)c2ccccc2)cs1

InChI Key InChIKey=IOPFZPQJWJQACY-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50091901   

TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50091901(1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl...)
Affinity DataKi:  440nMAssay Description:In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D2 short form expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50091901(1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl...)
Affinity DataKi:  590nMAssay Description:In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50091901(1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl...)
Affinity DataKi:  610nMAssay Description:In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D2L stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50091901(1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl...)
Affinity DataKi:  1.19E+3nMAssay Description:In vitro displacement of [3H]spiperone from the cloned human dopamine receptor D3 stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50091901(1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl...)
Affinity DataKi:  1.25E+3nMAssay Description:In vitro displacement of [3H]- SCH 23390 from the dopamine receptor D1 of bovine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed