BDBM50091834 (R)-9-Chloro-8-trifluoromethyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxaline::CHEMBL305123

SMILES FC(F)(F)c1cc2NC[C@H]3CNCCN3c2cc1Cl

InChI Key InChIKey=CZHWKMIRTKUCSN-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091834   

Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091834((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a,5,6-hexahy...)
Affinity DataEC50:  19nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091834((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a,5,6-hexahy...)
Affinity DataKi:  17nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091834((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a,5,6-hexahy...)
Affinity DataKi:  92nMAssay Description:Binding affinity using [3H]mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed