BDBM50091813 4-Ethyl-pyridin-2-ylamine::4-ethylpyridin-2-amine::CHEMBL62077

SMILES CCc1ccnc(N)c1

InChI Key InChIKey=SJWHILBZPGQBJE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50091813   

TargetNitric oxide synthase, endothelial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091813(4-ethylpyridin-2-amine | 4-Ethyl-pyridin-2-ylamine...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091813(4-ethylpyridin-2-amine | 4-Ethyl-pyridin-2-ylamine...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091813(4-ethylpyridin-2-amine | 4-Ethyl-pyridin-2-ylamine...)
Affinity DataIC50: 4.30E+3nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50091813(4-ethylpyridin-2-amine | 4-Ethyl-pyridin-2-ylamine...)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091813(4-ethylpyridin-2-amine | 4-Ethyl-pyridin-2-ylamine...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091813(4-ethylpyridin-2-amine | 4-Ethyl-pyridin-2-ylamine...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed