BDBM50091575 5-(7,7-Dimethyl-2-oxo-bicyclo[2.2.1]hept-1-ylmethanesulfonylamino)-3-(3-methyl-2-{[2-(1-methyl-1H-indol-3-yl)-ethylcarbamoyl]-methyl}-butyrylamino)-4-oxo-pentanoic acid::CHEMBL112207

SMILES CC(C)[C@H](CC(=O)NCCc1cn(C)c2ccccc12)C(=O)NC(CC(O)=O)C(=O)CNS(=O)(=O)CC12CCC(CC1=O)C2(C)C

InChI Key InChIKey=YVDYEVYYQUUDIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091575   

TargetCaspase-1(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091575(5-(7,7-Dimethyl-2-oxo-bicyclo[2.2.1]hept-1-ylmetha...)
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed