BDBM50091537 4-tert-Butyl-N-[5-hydroxymethyl-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-benzenesulfonamide::CHEMBL55876

SMILES COc1cccc(Sc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)noc2CO)c1

InChI Key InChIKey=WXVBYWXZJXXJDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091537   

TargetEndothelin receptor type B(Pig)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091537(4-tert-Butyl-N-[5-hydroxymethyl-4-(3-methoxy-pheny...)
Affinity DataIC50: 560nMAssay Description:Binding affinity towards displacement of [125 I] ET-3 from COS-7 cells transfected with porcine Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091537(4-tert-Butyl-N-[5-hydroxymethyl-4-(3-methoxy-pheny...)
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of [125 I] ET-1 from rat aortic smooth muscle A7r5 cells transfected with Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed