BDBM50091527 4-tert-Butyl-N-[4-(3-methoxy-phenylsulfanyl)-5-(3-oxo-propyl)-isoxazol-3-yl]-benzenesulfonamide::CHEMBL54773

SMILES COc1cccc(Sc2c(CCC=O)onc2NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1

InChI Key InChIKey=LBBUNWJQUYVSLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091527   

TargetEndothelin-1 receptor(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091527(4-tert-Butyl-N-[4-(3-methoxy-phenylsulfanyl)-5-(3-...)
Affinity DataIC50: 380nMAssay Description:Displacement of [125 I] ET-1 from rat aortic smooth muscle A7r5 cells transfected with Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091527(4-tert-Butyl-N-[4-(3-methoxy-phenylsulfanyl)-5-(3-...)
Affinity DataIC50: 500nMAssay Description:Binding affinity towards displacement of [125 I] ET-3 from COS-7 cells transfected with porcine Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed