BDBM50091386 1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethanone::CHEMBL114129::CHEMBL128851

SMILES CC(=O)c1ccc(OCCCc2cnc[nH]2)cc1

InChI Key InChIKey=FDJSGXRROVCWFT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091386   

TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50091386(CHEMBL128851 | CHEMBL114129 | 1-{4-[3-(1H-Imidazol...)
Affinity DataKi:  0.800nMAssay Description:Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50091386(CHEMBL128851 | CHEMBL114129 | 1-{4-[3-(1H-Imidazol...)
Affinity DataKi:  0.800nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50091386(CHEMBL128851 | CHEMBL114129 | 1-{4-[3-(1H-Imidazol...)
Affinity DataKi:  29nMAssay Description:Binding affinity to rat Histamine H3 receptor in CHO-K1 cells using [125I]iodoproxyfan as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50091386(CHEMBL128851 | CHEMBL114129 | 1-{4-[3-(1H-Imidazol...)
Affinity DataKi:  87nMAssay Description:Inhibition of [125I]iodoproxyfan binding to human histamine H3 receptor of CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed