BDBM50091334 CHEMBL3582252

SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN1CCCC[C@H]1C(O)=O

InChI Key InChIKey=ZBOYJODMIAUJHH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50091334   

TargetProgrammed cell death 1 ligand 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50091334(CHEMBL3582252)
Affinity DataIC50: 6nMAssay Description:Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091334(CHEMBL3582252)
Affinity DataIC50: 80nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction after 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091334(CHEMBL3582252)
Affinity DataIC50: 92nMAssay Description:Inhibition of PD-1/PDL1 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091334(CHEMBL3582252)
Affinity DataIC50: 76nMAssay Description:Inhibition of PD1/PD-L1 (unknown origin) protein-protein interaction measured after 135 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50091334(CHEMBL3582252)
Affinity DataIC50: 202nMAssay Description:Inhibition of PD-1 binding to human PD-L1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed