BDBM50091332 CHEMBL3582254::US9872852, Example 79

SMILES C[C@@H](NCc1ccc(OCc2cccc(c2C)-c2ccccc2)c(Cl)c1)C(O)=O

InChI Key InChIKey=QGXJVELKPSMEGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091332   

TargetProgrammed cell death 1 ligand 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50091332(CHEMBL3582254 | US9872852, Example 79)
Affinity DataIC50: 6nMAssay Description:Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50091332(CHEMBL3582254 | US9872852, Example 79)
Affinity DataIC50: 53nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
Go to US Patent