BDBM50091192 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-quinoline::CHEMBL110446::x3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-quinoline

SMILES CS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1cnc2ccccc2c1)C(F)(F)F

InChI Key InChIKey=QNEDJHHKBRZHMD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091192   

TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091192(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091192(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091192(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 631nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50091192(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 6.30E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed