BDBM50091191 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-5-methoxy-pyridine::CHEMBL320118

SMILES COc1cncc(c1)-c1nc(cn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=OGFKQCWFODPUOX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091191   

TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091191(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091191(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50091191(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 2.69E+7nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed