BDBM50091178 2-(4-Bromo-thiophen-2-yl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole::CHEMBL110382

SMILES CS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1cc(Br)cs1)C(F)(F)F

InChI Key InChIKey=HVSYEMBOCDOJFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091178   

TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091178(2-(4-Bromo-thiophen-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091178(2-(4-Bromo-thiophen-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091178(2-(4-Bromo-thiophen-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataIC50: 25.7nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed