BDBM50091177 1-(4-Methanesulfonyl-phenyl)-2-(3-methyl-thiophen-2-yl)-4-trifluoromethyl-1H-imidazole::CHEMBL110876

SMILES Cc1ccsc1-c1nc(cn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=WRSSNSVRVLLXGC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091177   

TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091177(1-(4-Methanesulfonyl-phenyl)-2-(3-methyl-thiophen-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091177(1-(4-Methanesulfonyl-phenyl)-2-(3-methyl-thiophen-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091177(1-(4-Methanesulfonyl-phenyl)-2-(3-methyl-thiophen-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50091177(1-(4-Methanesulfonyl-phenyl)-2-(3-methyl-thiophen-...)
Affinity DataIC50: 9.12E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed