BDBM50091171 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-pyridine::CHEMBL325755

SMILES CS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1cccnc1)C(F)(F)F

InChI Key InChIKey=ZJOUYQCSZYKGKU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50091171   

TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091171(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091171(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091171(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50091171(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 5.88E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091171(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of recombinant human COX-2 expressed in Baculovirus infected sf9 cells using arachidonic acid as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed