BDBM50091046 CHEMBL3582112

SMILES Cc1noc(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCc12

InChI Key InChIKey=YCRPDBNNDVYMBL-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50091046   

TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091046(CHEMBL3582112)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human glucocorticoid receptor transfected in CHOK1 cells assessed as inhibition of dexamethasone-induced receptor transcriptio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091046(CHEMBL3582112)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-dexamethasone from cytosolic fraction of human recombinant glucocorticoid receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091046(CHEMBL3582112)
Affinity DataKi:  1.48E+3nMAssay Description:Displacement of [3H]-progesterone from cytosolic fraction of human recombinant progesterone-B receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091046(CHEMBL3582112)
Affinity DataKi: >2.30E+3nMAssay Description:Displacement of fluormone ES2 from human recombinant estrogen receptor-alpha expressed in insect Sf9 cells after 120 mins by fluorescence polarizatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091046(CHEMBL3582112)
Affinity DataKi: >2.30E+3nMAssay Description:Displacement of fluormone ES2 from human recombinant estrogen receptor-beta expressed in insect Hi5 cells after 120 mins by fluorescence polarization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091046(CHEMBL3582112)
Affinity DataKi: >2.30E+3nMAssay Description:Displacement of [3H]methyltrienolone from cytosolic fraction of androgen receptor in human LANCAP cells after 24 hrs by scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091046(CHEMBL3582112)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]-aldosterone from cytosolic fraction of human recombinant mineralocorticoid receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed