BDBM50091009 2-[5-Guanidino-2-(5-guanidino-2-{[2-(8-hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2,6-methano-benzo[d]azocin-3-ylmethyl)-1-phenyl-cyclopropanecarbonyl]-amino}-pentanoylamino)-pentanoylamino]-3-methyl-pentanoic acid methyl ester(MPCB-RRI)::CHEMBL408096

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@]1(C[C@@H]1CN1CC[C@]2(C)C(C)C1Cc1ccc(O)cc21)c1ccccc1)C(=O)OC

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091009   

TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50091009(2-[5-Guanidino-2-(5-guanidino-2-{[2-(8-hydroxy-6,1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50091009(2-[5-Guanidino-2-(5-guanidino-2-{[2-(8-hydroxy-6,1...)
Affinity DataKi:  4.60E+3nMAssay Description:Displacement of [3H]diprenorphine from opioid receptor mu 1 on crude membrane fractions obtained from whole rat brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50091009(2-[5-Guanidino-2-(5-guanidino-2-{[2-(8-hydroxy-6,1...)
Affinity DataKi: >2.50E+4nMAssay Description:Displacement of [3H]diprenorphine opioid receptor delta 1 on crude membrane fractions obtained from the whole rat brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed