BDBM50090990 2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2,6-methano-benzo[d]azocin-3-ylmethyl)-1-phenyl-cyclopropanecarboxylic acid {[3-methyl-1-(5-pentanimidoylamino-pentylcarbamoyl)-butylcarbamoyl]-methyl}-amide::CHEMBL318532

SMILES CCCCC(=N)NCCCCCNC(=O)C(CC(C)C)NC(=O)CNC(=O)[C@@]1(CC1CN1CC[C@]2(C)C(C)C1Cc1ccc(O)cc21)c1ccccc1

InChI Key InChIKey=JAKVDGNIPIFHSH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090990   

TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50090990(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50090990(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  2.53E+3nMAssay Description:Displacement of [3H]diprenorphine from opioid receptor mu 1 on crude membrane fractions obtained from whole rat brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50090990(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  2.75E+3nMAssay Description:Displacement of [3H]diprenorphine opioid receptor delta 1 on crude membrane fractions obtained from the whole rat brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed