BDBM50090856 (2R,3R,4S,5R)-2-(4-Amino-5-bromo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-ethyl-tetrahydro-furan-3,4-diol::(2R,3R,4S,5R)-2-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-ethyl-tetrahydrofuran-3,4-diol::2-(4-Amino-5-bromo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-ethyl-tetrahydro-furan-3,4-diol::CHEMBL95721

SMILES CC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12

InChI Key InChIKey=GTVNVNVXUOYNCL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090856   

TargetAdenosine kinase(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50090856((2R,3R,4S,5R)-2-(4-amino-5-bromo-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50090856((2R,3R,4S,5R)-2-(4-amino-5-bromo-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human adenosine kinase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50090856((2R,3R,4S,5R)-2-(4-amino-5-bromo-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 501nMAssay Description:Concentration required for 50% inhibition of the adenosine kinase (AK) activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed