BDBM50090692 1-Ethyl-7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-one::1-ethyl-7-methyl-2-phenyl-1,8-naphthyridin-4(1H)-one::CHEMBL415697

SMILES CCn1c(cc(=O)c2ccc(C)nc12)-c1ccccc1

InChI Key InChIKey=FWHOTNQFRIOUCV-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50090692   

TargetAdenosine receptor A1(Bovine)
Università

Curated by ChEMBL
LigandPNGBDBM50090692(1-Ethyl-7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-o...)
Affinity DataKi:  450nMAssay Description:Binding affinity against adenosine A1 receptor in bovine cortical membranes using [3H]CHA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Università

Curated by ChEMBL
LigandPNGBDBM50090692(1-Ethyl-7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-o...)
Affinity DataKi:  450nMAssay Description:Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50090692(1-Ethyl-7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against adenosine A1 receptor in human cortical membranes using [3H]CHA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50090692(1-Ethyl-7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against adenosine A2 receptor in human striatal membranes using [3H]CGS-21680 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50090692(1-Ethyl-7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against adenosine A2 receptor in bovine striatal membranes using [3H]-CGS-21,680 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50090692(1-Ethyl-7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from rat testis membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50090692(1-Ethyl-7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace the specific binding of [3H]-CGS- to adenosine A2A receptor form bovine brain striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed