BDBM50090449 2-(4-Chloro-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino)-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL42204::ethyl 2-(4-chlorophenyl)-4-(3-methyl-2,5-dioxo-2H-pyrrol-1(5H)-ylamino)pyrimidine-5-carboxylate

SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccc(Cl)cc1

InChI Key InChIKey=BQSQYQQCGHOGDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090449   

TargetProtein c-Fos/Transcription factor Jun(Human)
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090449(ethyl 2-(4-chlorophenyl)-4-(3-methyl-2,5-dioxo-2H-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed