BDBM50090434 4-(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino)-2-trifluoromethyl-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL43619::ethyl 4-(3,4-dimethyl-2,5-dioxo-2H-pyrrol-1(5H)-ylamino)-2-(trifluoromethyl)pyrimidine-5-carboxylate

SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C(C)=C(C)C1=O)C(F)(F)F

InChI Key InChIKey=TUKBVGOWAQPNFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090434   

TargetProtein c-Fos/Transcription factor Jun(Human)
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090434(ethyl 4-(3,4-dimethyl-2,5-dioxo-2H-pyrrol-1(5H)-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed