BDBM50090368 3-(4-Benzyloxy-phenyl)-N-hydroxy-3-(4-methoxy-benzenesulfonyl)-propionamide::CHEMBL42481

SMILES COc1ccc(cc1)S(=O)(=O)C(CC(=O)NO)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=VUAHLIXSRRYNJX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090368   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090368(3-(4-Benzyloxy-phenyl)-N-hydroxy-3-(4-methoxy-benz...)
Affinity DataIC50: 520nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090368(3-(4-Benzyloxy-phenyl)-N-hydroxy-3-(4-methoxy-benz...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090368(3-(4-Benzyloxy-phenyl)-N-hydroxy-3-(4-methoxy-benz...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090368(3-(4-Benzyloxy-phenyl)-N-hydroxy-3-(4-methoxy-benz...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed