BDBM50090358 3-Biphenyl-4-yl-N-hydroxy-3-(4-methoxy-benzenesulfonyl)-propionamide::CHEMBL295660

SMILES COc1ccc(cc1)S(=O)(=O)C(CC(=O)NO)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=OUYWTARRIITHBX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090358   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090358(3-Biphenyl-4-yl-N-hydroxy-3-(4-methoxy-benzenesulf...)
Affinity DataIC50: 3.60E+3nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090358(3-Biphenyl-4-yl-N-hydroxy-3-(4-methoxy-benzenesulf...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090358(3-Biphenyl-4-yl-N-hydroxy-3-(4-methoxy-benzenesulf...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090358(3-Biphenyl-4-yl-N-hydroxy-3-(4-methoxy-benzenesulf...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed