BDBM50090355 7-Benzo[1,3]dioxol-5-yl-3-(3,4-dimethoxy-benzenesulfonyl)-heptanoic acid hydroxyamide::CHEMBL42449

SMILES COc1ccc(cc1OC)S(=O)(=O)C(CCCCc1ccc2OCOc2c1)CC(=O)NO

InChI Key InChIKey=QXMYNGZVAQOGPB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090355   

TargetInterstitial collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090355(7-Benzo[1,3]dioxol-5-yl-3-(3,4-dimethoxy-benzenesu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090355(7-Benzo[1,3]dioxol-5-yl-3-(3,4-dimethoxy-benzenesu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090355(7-Benzo[1,3]dioxol-5-yl-3-(3,4-dimethoxy-benzenesu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090355(7-Benzo[1,3]dioxol-5-yl-3-(3,4-dimethoxy-benzenesu...)
Affinity DataIC50: 6.40nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed