BDBM50090346 3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-hydroxy-3-[3-(4-methoxy-phenoxy)-phenyl]-propionamide::CHEMBL42104

SMILES COc1ccc(Oc2cccc(c2)C(CC(=O)NO)S(=O)(=O)c2ccc(OC)c(OC3CCCC3)c2)cc1

InChI Key InChIKey=OHZWWRAGTGIQOP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090346   

TargetInterstitial collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090346(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090346(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090346(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090346(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)
Affinity DataIC50: 49nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed