BDBM50090172 (R)-2-[4-(2,3-Dimethyl-1-oxa-9-thia-cyclopenta[b]fluoren-4-yl)-2,6-diiodo-phenoxy]-3-phenyl-propionic acid::CHEMBL39626

SMILES Cc1oc2cc3sc4ccccc4c3c(-c3cc(I)c(O[C@H](Cc4ccccc4)C(O)=O)c(I)c3)c2c1C

InChI Key InChIKey=HPFPSGLWBHMGHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090172   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50090172((R)-2-[4-(2,3-Dimethyl-1-oxa-9-thia-cyclopenta[b]f...)
Affinity DataIC50: 74nMAssay Description:Compound was evaluated for the inhibitory activity against recombinant Protein-tyrosine phosphatase 1B using, phosphotyrosyl dodecapeptide [TRDI(P)YE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50090172((R)-2-[4-(2,3-Dimethyl-1-oxa-9-thia-cyclopenta[b]f...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant PTP1B (1 to 321 residues) expressed in Escherichia coli using TRDIYETDYYRK as peptide substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed