BDBM50090171 (R)-2-[4-(2,3-Dimethyl-1-oxa-9-thia-cyclopenta[b]fluoren-4-yl)-2,6-diiodo-phenoxy]-propionic acid::CHEMBL290295

SMILES C[C@@H](Oc1c(I)cc(cc1I)-c1c2c(C)c(C)oc2cc2sc3ccccc3c12)C(O)=O

InChI Key InChIKey=SSRKUSZKMXQVTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090171   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50090171((R)-2-[4-(2,3-Dimethyl-1-oxa-9-thia-cyclopenta[b]f...)
Affinity DataIC50: 284nMAssay Description:Compound was evaluated for the inhibitory activity against recombinant Protein-tyrosine phosphatase 1B using, phosphotyrosyl dodecapeptide [TRDI(P)YE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50090171((R)-2-[4-(2,3-Dimethyl-1-oxa-9-thia-cyclopenta[b]f...)
Affinity DataIC50: 284nMAssay Description:Inhibition of human recombinant PTP1B (1 to 321 residues) expressed in Escherichia coli using TRDIYETDYYRK as peptide substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed