BDBM50090060 1-(4-Bromo-phenyl)-6-phenyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL93893

SMILES NC1=NC(N(C(N)=N1)c1ccc(Br)cc1)c1ccccc1

InChI Key InChIKey=KTIIBCZDEGUAEF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090060   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(malaria parasite P. falciparum)
National Center For Genetic Engineering and Biotechnology At Thailand

Curated by ChEMBL
LigandPNGBDBM50090060(1-(4-Bromo-phenyl)-6-phenyl-1,6-dihydro-[1,3,5]tri...)
Affinity DataKi:  2.90nMAssay Description:Evaluated for inhibition constant (Ki wt) against Wild-type dihydrofolate reductase of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase [A16V,S108T](malaria parasite P. falciparum)
National Center For Genetic Engineering and Biotechnology At Thailand

Curated by ChEMBL
LigandPNGBDBM50090060(1-(4-Bromo-phenyl)-6-phenyl-1,6-dihydro-[1,3,5]tri...)
Affinity DataKi:  90nMAssay Description:Evaluated for inhibition constant (Ki mut) against A16V+S108T Mutant dihydrofolate reductase of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed