BDBM50090004 CHEMBL269377::[D-Pro2] Dynorphin A (1-11)-NH2H-Tyr-D-Pro-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=VZFYSSABILOIGC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090004   

TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090004([D-Pro2] Dynorphin A (1-11)-NH2H-Tyr-D-Pro-Gly-Phe...)
Affinity DataKi:  65nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090004([D-Pro2] Dynorphin A (1-11)-NH2H-Tyr-D-Pro-Gly-Phe...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090004([D-Pro2] Dynorphin A (1-11)-NH2H-Tyr-D-Pro-Gly-Phe...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed