BDBM50089912 (2S)-2-amino-4-methylidenepentanedioic acid::4-methylene-L-glutamic acid::CHEMBL38499

SMILES N[C@@H](CC(=C)C(O)=O)C(O)=O

InChI Key InChIKey=RCCMXKJGURLWPB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50089912   

TargetMetabotropic glutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089912((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...)
Affinity DataKi:  150nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089912((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...)
Affinity DataKi:  230nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50089912((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...)
Affinity DataKi:  270nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 5 using HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50089912((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...)
Affinity DataKi:  450nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 6 using HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetVesicular glutamate transporter 3(Rat)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50089912((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...)
Affinity DataKi:  3.00E+3nMAssay Description:Evaluated for competitive inhibition against Vesicular glutamate transporter (VGLUT), and Ki value was reported.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089912((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...)
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed