BDBM50089759 (R)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanol::CHEMBL280974

SMILES O[C@@H](CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1

InChI Key InChIKey=GGUSQTSTQSHJAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089759   

TargetN-methyl-D-aspartate receptor(Pig)
Zentrum FüR Pharmaforschung

Curated by ChEMBL
LigandPNGBDBM50089759((R)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...)
Affinity DataIC50: 213nMAssay Description:Compound was tested for inhibition of [3H]MK-801 binding to N-methyl-D-aspartate glutamate receptor at NR2B subunit in high affinity fraction of porc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-methyl-D-aspartate receptor(Pig)
Zentrum FüR Pharmaforschung

Curated by ChEMBL
LigandPNGBDBM50089759((R)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]ifendropil from binding site of N-methyl-D-aspartate glutamate receptor was evaluated employing synaptosomal fraction of porcine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN-methyl-D-aspartate receptor(Pig)
Zentrum FüR Pharmaforschung

Curated by ChEMBL
LigandPNGBDBM50089759((R)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...)
Affinity DataIC50: 2.37E+4nMAssay Description:Compound was tested for inhibition of [3H]MK-801 binding to N-methyl-D-aspartate glutamate receptor lacking NR2B subunit in low affinity fraction of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed