BDBM50089456 CHEMBL32996::N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[5-(3-oxo-3-pyrrolidin-1-yl-propyl)-[1,2,4]oxadiazol-3-yl]-benzenesulfonamide

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2noc(CCC(=O)N3CCCC3)n2)cc1)c1cccnc1

InChI Key InChIKey=ZNVSBFVJADWRNG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089456   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089456(N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataIC50: 5.10E+4nMAssay Description:Binding affinity towards Beta-2 adrenergic receptor prepared from CHO cells expressing the cloned human receptor in the presence of [125I]iodocyanopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089456(N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity towards cloned human Beta-1 adrenergic receptor prepared from CHO cells in the presence of [125I]iodocyanopindololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089456(N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataEC50:  120nMAssay Description:Agonist activity as increasedn cAMP production in Chinese hamster ovary (CHO)cells expressing human beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed