BDBM50089367 CHEMBL3577949

SMILES COC[C@@H]1C[C@@H](CC[C@@H]1N1CC[C@H](Nc2ncnc3ccc(cc23)C(F)(F)F)C1=O)N(C)C(C)C

InChI Key InChIKey=QJQMEUAVQLMKRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089367   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50089367(CHEMBL3577949)
Affinity DataIC50: 3nMT: 2°CAssay Description:Inhibition of [125I]hMCP1 binding to CCR2 in human PBMC incubated for 30 mins at room temperatureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50089367(CHEMBL3577949)
Affinity DataIC50: 18nMAssay Description:Inhibition of [125I]MCP1-beta binding to CCR5 in human HT1080 cell membranes incubated for 4 to 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed