BDBM50089228 CHEMBL3577873

SMILES CCNC(=O)N1CCC(CC1)Nc1ncc2ccc(=O)n(C(C)C)c2n1

InChI Key InChIKey=YTNDEFNPJUZDTP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089228   

TargetMitogen-activated protein kinase 8(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50089228(CHEMBL3577873)
Affinity DataIC50: 85nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50089228(CHEMBL3577873)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50089228(CHEMBL3577873)
Affinity DataIC50: 114nMAssay Description:Inhibition of JNK2 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50089228(CHEMBL3577873)
Affinity DataIC50: 54nMAssay Description:Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed