BDBM50089225 CHEMBL3577877

SMILES CC(C)NC(=O)NC1CCC(CC1)Nc2ncc3c(n2)N(C(=O)C=C3)C4CCCC4

InChI Key InChIKey=QJPUIIKZKMYPSK-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089225   

TargetMitogen-activated protein kinase 8(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50089225(CHEMBL3577877)
Affinity DataIC50: 7nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50089225(CHEMBL3577877)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50089225(CHEMBL3577877)
Affinity DataIC50: 12nMAssay Description:Inhibition of JNK2 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50089225(CHEMBL3577877)
Affinity DataIC50: 11nMAssay Description:Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)