BDBM50089196 3-Benzenesulfonyl-heptanoic acid hydroxyamide::CHEMBL263501

SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccccc1

InChI Key InChIKey=TUUMURVUDGZZQZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50089196   

TargetNeprilysin(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against neutral endopeptidase enzyme (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50: 22nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed