BDBM50089187 (2R,4S)-4-(4'-fluoro-1,1'-biphenyl-4-yl)-N-hydroxy-5-oxopyrrolidine-2-carboxamide::4-(4'-Fluoro-biphenyl-4-yl)-5-oxo-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL20160

SMILES ONC(=O)[C@H]1C[C@H](C(=O)N1)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=CGAZROFVKJRMSR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089187   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187(4-(4'-Fluoro-biphenyl-4-yl)-5-oxo-pyrrolidine-2-ca...)
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187(4-(4'-Fluoro-biphenyl-4-yl)-5-oxo-pyrrolidine-2-ca...)
Affinity DataIC50: 182nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187(4-(4'-Fluoro-biphenyl-4-yl)-5-oxo-pyrrolidine-2-ca...)
Affinity DataIC50: 182nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187(4-(4'-Fluoro-biphenyl-4-yl)-5-oxo-pyrrolidine-2-ca...)
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed