BDBM50089186 (2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-2-carboxamide::4-Naphthalen-2-yl-5-oxo-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL20287

SMILES ONC(=O)[C@H]1C[C@H](C(=O)N1)c1ccc2ccccc2c1

InChI Key InChIKey=RGNRNPIPRYODKL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089186   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed