BDBM50089182 (2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-2-carboxylic acid hydroxyamide::4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL279482

SMILES ONC(=O)[C@H]1C[C@H](C(=O)N1)c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=TUIHSDQRXNNCLL-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50089182   

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 82nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 82nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of matrix metalloprotease -2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 703nMAssay Description:Inhibition of matrix metalloprotease -3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed