BDBM50089085 CHEMBL3577694

SMILES CN1C2N(CCc3c2[nH]c2ccc(O)cc32)C(=O)c2cc(NCc3ccc(cc3)-c3noc(CCCCCCC(=O)NO)n3)ccc12

InChI Key InChIKey=FTVNKVXRXIRGTC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089085   

TargetHistone deacetylase 8(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089085(CHEMBL3577694)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089085(CHEMBL3577694)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089085(CHEMBL3577694)
Affinity DataIC50: 275nMAssay Description:Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089085(CHEMBL3577694)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed